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KMID : 0191120090240030488
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Journal of Korean Medical Science
2009 Volume.24 No. 3 p.488 ~ p.492
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Stereotactic Body Radiotherapy for Isolated Para-aortic Lymph Node Recurrence after Curative Resection in Gastric Cancer
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Kim Mi-Sook
Yoo Sung-Yul
Cho Chul-Koo
Yoo Hyung-Jun
Yang Kwang-Mo
Kang Jin-Kyu
Lee Dong-Han
Lee Jong-Inn
Bang Ho-Youn
Kim Min-Suk
Kang Hae-Jin
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Abstract
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The aim of this study was to investigate whether stereotactic body radiotherapy (SBRT) can salvage gastric cancer patients with para-aortic lymph node (PALN) recurrence. From January 2003 to December 2006, 7 patients were treated for isolated PALN recurrence from gastric cancer after curative resection. Follow up durations ranged from 19 to 33 months (median; 26 months), and SBRT doses from 45 Gy to 51 Gy (median 48 Gy) in 3 fractions. Disease progression-free and overall survivals and toxicities were recorded. Response to treatment was assessed by computed tomography. Final patient outcomes were as follows: 2 were alive without evidence of disease, 3 remained alive with disease, and 2 patients died of disease. Five of 7 patients showed complete response and 2 patients partial response between 3 and 11 months after SBRT. Three-year overall and disease progression-free survival rates post-SBRT were 43% and 29%, respectively. No severe complication was detected during follow-up. Selected patients with isolated PALN recurrence can be salvaged by SBRT without severe complications.
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KEYWORD
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Stomach Neoplasms, Recurrence, Radiotherapy
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